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Amsterdam study: ECCS/ERS predictions do not fit well

In a study of 1112 males and 1345 females who had no respiratory symptoms (smokers and non-smokers) findings on FEV1 and FVC were as follows (mean and standard deviation):

Index males females
FVC % predicted 108 ± 16 117 ± 18
FEV1 % predicted 102 ± 18 108 ± 18

Smoking affects pulmonary function unfavorably, in particular in males. Taking that into account the findings in Amsterdam agree well with those in asymptomatic nonsmokers in another large-scale study of a representative sample of the population of Vlaardingen (urban) and Vlagtwedde (rural).

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