Question 1
What is the difference between specific and non-specific bronchial responsiveness?
Specific responsiveness relates to specific
stimuli, such as cold air, allergens, physical or toxic
stimuli.- Non-specific responsiveness relates to
airway responses elicited by unknown stimuli.
- Specific responsiveness implies bronchoconstriction
when challenged with histamine or methacholine.
- Specific bronchial responsiveness implies
a bronchoconstrictive response when challenged with allergens.