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Optimal prediction of spirometric indices

Changing body proportions from infancy to adulthoodFrom birth to adolescence leg length grows faster than trunk height. This process comes to an end at about the age of sexual maturity. It will therefore not come as a surprise that lung volume, a component of the contents of the trunk, cannot be predicted solely on the basis of standing height; somehow age should enter into the equation.
The prediction of lung volumes is appreciably improved by taking interaction between age and standing height into account. This eliminates any residual trend between residual and age. In boys a weak age-related trend remains, but it is small and quite acceptable for practical purposes. The prediction equation is of the form:

loge(FVC) or loge(FEV1) = a + (b + c·age)·height.

It was developed from analysis of data from 2269 girls and 3592 boys from England, Italy, the Netherlands, Austria and Spain (ref. 1). The equation fits each of the geographical subsets of children and adolescents and is valid for girls between ages 6-16 yr, and boys between 6-18 yr. The resulting equations are given in the next page.

Satisfactory prediction of FEV1 in children and adolescents

See also:
Reference values for adults
SpirXpert software

Ref. 1 - Reference values for children and adolescents
  Quanjer PhH, Borsboom GJJM, Brunekreef B, Zach M, Forche G, Cotes JE, Sanchis J, Paoletti P. Spirometric reference values for white European children and adolescents: Polgar revisited. Pediat Pulmonol 1995; 19: 135-142.
   
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